Boronic acid derivatives
Cayman Chemical CAY10455 Fatty Acids and Deriv
A fluorescent substrate for AEA transport; cleavage by intracellular esterases gives a bright fluorescence at 530 nm
Cayman Chemical CAY10434 Fatty Acids and Deriv
A selective inhibitor of the 20-HETE synthase CYP4A11 (IC50 = 8.8 nM human renal microsomes)
Sigma Aldrich Fine Chemicals Biosciences Cyclohexylboronic acid >=95% | 4441-56-9 | MFCD01311824 | 10G
Cyclohexylboronic acid >=95% | Purity: >=95% | Mol Wt: 127.98 | 4441-56-9 | MFCD01311824 | 10G
Cayman Chemical 17 SHDHA Fatty Acids and Deriv
A hydroxy fatty acid formed from DHA by 15-LO and is a precursor to 17(S)-resolvins; inhibits platelet 12-LO (IC50 = 0.4 μM); inhibits TNF-α-induced expression of IL1B in a human glial cell line (IC50 = ~0.5 nM); inhibits NLRP3 inflammasome formation induced by homocysteine in podocytes at 100 nM
Cayman Chemical 17 SHDHA Fatty Acids and Deriv
A hydroxy fatty acid formed from DHA by 15-LO and is a precursor to 17(S)-resolvins; inhibits platelet 12-LO (IC50 = 0.4 μM); inhibits TNF-α-induced expression of IL1B in a human glial cell line (IC50 = ~0.5 nM); inhibits NLRP3 inflammasome formation induced by homocysteine in podocytes at 100 nM
Cayman Chemical CAY10443 Fatty Acids and Deriv
A pro-apoptotic activator of the apoptosome; activates caspase-3 (EC50 = 5 µM) in a cell-free assay
Cayman Chemical 17 SHDHA Fatty Acids and Deriv
A hydroxy fatty acid formed from DHA by 15-LO and is a precursor to 17(S)-resolvins; inhibits platelet 12-LO (IC50 = 0.4 μM); inhibits TNF-α-induced expression of IL1B in a human glial cell line (IC50 = ~0.5 nM); inhibits NLRP3 inflammasome formation induced by homocysteine in podocytes at 100 nM
Cayman Chemical CAY10485 Fatty Acids and Deriv
An ACAT-1 and -2 inhibitor with antioxidant activity; inhibits human ACAT-1 and ACAT-2 (IC50s = 95 and 81 µM, respectively); inhibits cooper-mediated oxidation of LDL by 91% at 2 µM
Cayman Chemical 17 SHETE Fatty Acids and Deriv
A potent inhibitor of proximal tubule ATPase activity; is a CYP450 metabolite of arachidonic acid; inhibits proximal tubule ATPase activity by 70% at 2 µM
Cayman Chemical CAY10509 Fatty Acids and Deriv
Derivative of PGF1α containing a thio-fluorobenzene substituent in the lower side chain; binds to the recombinant human FP receptor with an IC50 value of about 30 nM
Cayman Chemical 9OxoOTrE Fatty Acids and Deriv
9-OxoOTrE is produced by the oxidation of 9-HpOTrE.{14394} 9-OxoOTrE exhibits antimicrobial activity against plant pathogenic microorganisms including bacteria and fungi.{14395}
Cayman Chemical CAY10509 Fatty Acids and Deriv
Derivative of PGF1α containing a thio-fluorobenzene substituent in the lower side chain; binds to the recombinant human FP receptor with an IC50 value of about 30 nM
Cayman Chemical 19 RHETE Fatty Acids and Deriv
A potent vasodilator of renal arterioles; 30% of the metabolite composition of arachidonic acid by CYP2E1; potent vasodilator of renal preglomerular vessels; blocks 20-HETE-induced vasoconstriction of renal arterioles at 1 µM
Cayman Chemical 8 9EpETE Fatty Acids and Deriv
An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo
